當(dāng)前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 標(biāo)記一抗 > bs-10421R-HRPHRP標(biāo)記的磷酸化Nemo樣激酶抗體
簡要描述:Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. (referenced from swissprot)